The Application of Amorphous Block in Biotech and Medical Device Field
Amorphous alloys block is widely used in the biomedical field, from orthopedics and cardiovascular to dental implants and fillings. Specifically, for example, non-biodegradable Ti-based, Zr-based and Fe-based amorphous alloys have excellent mechanical properties and good corrosion resistance, and can be used as biomedical equipment (such as scalpels, Pacemakers, medical staplers and minimally invasive surgical equipment) and biomedical implants (for example: forming joint curved surfaces, artificial prostheses, dental implants, which must work for a long time in a severe human body). On the other hand, biodegradable bulk amorphous alloys (including Mg-based, Ca-based, Zn-based and Sr-based amorphous alloys) have great potential as fracture repair materials (for example: intramedullary nails, bone plates and bone Screws) can also become cardiovascular stents, absorbent sutures, fillings around teeth, and bone fillings after tumors and cysts in joints are removed; as their temporary mission is completed, they are gradually degraded in the human body. During this time, blood vessels and bones are remodeled and healed.
Amorphous alloys for biomedicine have the combined properties of bioglass and biometal, and exhibit high strength and low modulus of elasticity, making them ideally suitable for biomedical applications in theory. In particular, the elastic limit of amorphous alloys for biomedicine is 2%, which is extremely high compared to the elastic limit of bones (1%), which is comparable to that of bones. This shows that amorphous alloys for biomedicine have unique elastic bending and bones. The natural bending of the amorphous alloy will cause the amorphous alloy to have a more uniform stress distribution than the existing materials, reduce stress concentration and reduce the stress shielding effect, so as to achieve faster recovery and healing of patients.
Due to the unique properties of amorphous alloys for biomedical applications, amorphous alloy bone screws can use thinner screw shafts and deeper threads, thereby providing greater bonding force between bad bones. Compared with the traditional 316L stainless steel phase stent, the amorphous alloy stent only needs 1/3 of its cross-sectional pillar and has more than 5 times the deflection. In the past few decades, some special amorphous alloys for biomedical purposes have been developed, and in vitro and in vivo tests and feasibility evaluations have been done as biomaterials.
In the past decade, many biomedical implants and devices using amorphous alloys as raw materials have been designed and developed. The biggest advantages of amorphous alloys:
1) More excellent casting surface quality;
2) The position and size between the containers are more accurate;
3) The difference between product batches is only limited by the changes before and after the mold cavity.
In addition to the biomedical devices mentioned above, bulk amorphous alloys have great potential as biomedical implants. According to reports, amorphous alloys can increase the strength, corrosion resistance, biocompatibility and service life of cardiovascular stents and orthopedic implants (such as bone plates, bone screws, joint connectors, artificial prostheses, Absorbable sutures, dental implants and fillers). Amorphous alloys consistent with the main constituent elements of traditional biomedical materials have been developed as potential biomedical materials, including Ti-based, Zr-based, Fe-based (well-known amorphous steel), Mg-based and Zn-based amorphous alloy. In addition, considering that the main elements Ca and Sr in Ca-based and Sr-based amorphous alloys are human nutritional elements, Ca-based and Sr-based amorphous alloys have also been developed as potential biodegradable materials.
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